It all started listening to a lecture that went unnoticed for Jef Boeke. The rapporteur was researcher at Stanford University Ronald Davis, recognized by his peers as a visionary scientist. But his words about the possibility of creating a yeast genome which were manufactured completely in a laboratory from the basic chemical DNA molecules purchased in plastic bottles not stimulated at all Boeke.
Boeke, who just changed his position at Johns Hopkins by management Langone Medical Center New York University, and Chandrasegaran just create the first chromosome complex made from scratch in the laboratory have shown that fulfills the same functions as one natural and does not interfere with the normal life of the leaven of bread ('Saccharomyces cerevisiae') which used as a model. The study, just published in the journal Science, is a scientific milestone that has been compared to those of skill in the sequencing of the human genome and that opens the door to the design of microorganisms capable of producing biofuels, vaccines, or many of the compounds used by the chemical industry.
But in reality represents a conceptual leap that goes far beyond. Current genomics, including synthetic advanced by scientists as the father of the human genome and author of the first artificial genome of a bacterium, Craig Venter, or by the controversial and brilliant researcher George Church of Harvard, has been based to date copies artificial nature of what has occurred over millions of years of evolution. However, regardless of the complexity of the mere fact of making the chromosome of a eukaryotic organism, whose cells have a nucleus where host DNA in chromosomes complex-ordered, the great contribution of Jef Boeke is precisely that 'their' chromosome differs largely on what natural selection has carved over millennia.
News published in the newspaper El Mundo, to see the full story go to the following link.